ABSTRACT
Evaluation of the Role of Itraconazole and Posaconazole in Viral Infection as Immunomodulatory Drugs
Matrix Science Medica (MSM)
Author: Letter to Editor
This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
The widespread therapeutic use of azole-based pharmaceutical drugs has given rise to multiple interests, and their research and development has become a very fast creation of a successful spotlight of infinite space. Itraconazole (ITZ) and posaconazole (POS) belong to triazole that have a broadspectrum antifungal agent. They commonly used to prevent and treat several fungal infections that cause superfiial, subcutaneous, and systemic infections.[3] These drugs have few side effects compared with other drugs. Since antifungal drugs are commonly used in patients who are to some extent immunocompromised, it is important to assess the potential effects of these therapies on the immune system. It has been proposed that the efficacy of some antifungal agents may be related to their capacity to induce cytokine production. This also confirmed that some antifungal drugs increase chemokine levels in the supernatants of human mononuclear cell cultures such as CCL3 and CCL4.
| Pages | 76-77 |
| Year | 2021 |
| Issue | 4 |
| Volume | 5 |
