Matrix Science Medica (MSM)

STUDY ON THE RELATION BETWEEN SELF CONSISTENCY AND CONGRUENCE AND MENTAL HEALTH OF POSTGRADUATES

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msm.01.2018.01.03

ABSTRACT

STUDY ON THE RELATION BETWEEN SELF CONSISTENCY AND CONGRUENCE AND MENTAL HEALTH OF POSTGRADUATES

Matrix Science Medica (MSM)
Author: Liu Chuanlei , Han Yuanfei , Li Guomin

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

DOI: 10.26480/msm.01.2018.01.03

Reveal the Relation between Self consistency and congruence and Mental Health of Postgraduates. Adopt self-consistency and congruence questionnaire, mental health questionnaire to carry out questionnaire investigation on 500 postgraduates of four Nanjing colleges and universities. Mental health of postgraduates has extremely negative notable relevance with the disharmony of oneself and experience and it has extremely negative notable relevance with self-flexibility. The degree of self consistency and congruence and self-flexibility of postgraduates with better psychological health situation is higher than that of postgraduates with poor mental health situation. Disharmony of oneself and experience, flexibility function of oneself forecast mentality symptom dissociation amounts to a certain extent. The degree of self-consistency and congruence has a significant influence on mental health.
Pages 1-3
Year 2018
Issue 1
Volume 2

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msm.02.2017.20.22

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PESTE DES PETITS RUMINANTS: AN OVERVIEW AND A CASE REPORT FROM PAKISTAN

Matrix Science Medica (MSM)
Author: Mughees Aizaz Alvi, Ali Hassan, Qaiser Tanveer, Arva Saleem, Warda Qamar

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

DOI: 10.26480/msm.02.2017.20.22

Peste des petits ruminants (PPR) is an acute or subacute viral disease of goats and sheep characterized by fever, necrotic stomatitis, gastroenteritis, pneumonia, and sometimes death. The virus also affects several wild small ruminant species. Cattle, buffalo, and pigs are only sub clinically infected. People are not at risk. The disease is of heavy economic significance in small ruminant industry and ranks among the top ten diseases affecting small ruminants. Isolation and quarantine measures, slaughtering of positive animals, proper disposal of infected materials, proper disinfection of utensils and other items of flock are crucial for control of PPR. PPR leads to heavy economic setbacks to the farmers. With the aims and objectives to flourish small ruminant farming and maximizing profit, a few key points should be rigorously adopted.
Pages 20-22
Year 2017
Issue 2
Volume 1

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msm.02.2017.16.19

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COMPARISON AND EVALUATION OF ONE-STEP REVERSE TRANSCRIPTASE-POLYMERASE CHAIN REACTION (RT-PCR) AND REVERSE TRANSCRIPTASE LOOP-MEDIATED ISOTHERMAL AMPLIFICATION ASSAY(RT-LAMP) FOR RAPID DETECTION OF FOOT-AND-MOUTH DISEASE VIRUS (FMDV)

Matrix Science Medica (MSM)
Author: Waqas Ali, Mudasser Habib, Sanaullah Sajid, Rai Shafqat Ali Khan, Muhammad Ashir Zia, Irfan Ullah Khan, Asad Javed, Hafiz Muhammad Muzammil, Muhammad Usman Mazhar, Muhammad Farooq, Muhammad Salah Ud Din Shah

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

DOI: 10.26480/msm.02.2017.16.19

Foot-and-mouth disease (FMD) is endemic in Pakistan and cause severe economic losses. Serotype O, A and Asia 1 is prevalent and their rapid detection for Pakistaniisolates is needed to determine the serotype prevalence in different areas of the country. One step reversetranscriptase-polymerase chain reaction (RT-PCR) and reverse transcriptase loop-mediated isothermal amplification (RT- LAMP) was compared for the rapid and sensitive detection of FMDV genome. FMDV genome was confirmed in 19/25clinically affected animals by sequencing. These positive samples (n=19) were also confirmed in both RT-PCR and RT-LAMP consensus assay.In theserotyping assay, RT-PCR detection rate was16.67%, 80%, and 50% and RT-LAMP detection rate was 50%, 60% and 50%for serotype Asia 1, O and type A respectively. In general detection of FMDV, RT-PCR assay and the RT-LAMP assay showed high concordance (k = 1.0). However, in serotype detection, RT-LAMP was found more sensitive as compared to RT-PCR for the detection of the FMDV serotype Asia1 and Vice Versa in the detection of serotype O. To the best of the author’s knowledge, this is thefirst document on thecomparison of RT-LAMP and one-step RT- PCR for FMDV using ESE-Quant Tube Scanner in Pakistan.The RT-LAMP assay has the potential for early and rapid clinical diagnosis, surveillance and serotyping of FMDV infection in endemic countries.
Pages 16-19
Year 2017
Issue 2
Volume 1

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msm.02.2017.13.15

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MEDICINAL EFFICACY OF ANTIHYPERTENSIVE AGENTS FOR ACUTE INFLAMMATION; AN ASSOCIATED RISK FACTOR OF HYPERTENSION

Matrix Science Medica (MSM)
Author: Muhammad Salman Sarwar, Zinayyera Subhani, Muhammad Bilal, Qura- tul-Ain Nazir

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

DOI: 10.26480/msm.02.2017.13.15

Hypertension is a lasting therapeutic complaint which can be kept in control by changing one’s dietary and lifestyle habits. Present study is based on identification of risk of acute pancreatitis which may occur with different doses of atenolol in Pakistani population. About 50% of our study population was administered with β-blockers. The β- blockers significantly decreased the levels of CRP (C- Reactive Protein) of test population. This observation strongly depicts high potential of beta blockers in stabilization of CRP levels and decreasing inflammatory response. In our study the patients were administered with many combinations with beta-blocker and their results showed that these combinations lower the CRP level in hypertensive patients. We conclude that antihypertensive also minimize the inflammation associated hypertension but not completely, as inflammation was reversed only in 67.5% population who were using beta-blocker. When treating hypertension, anti-inflammatory medicine treatment needs to be endorsed to successfully treat complaints and increase the communal and psychosomatic status of the patient.
Pages 13-15
Year 2017
Issue 2
Volume 1

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msm.02.2017.11.12

ABSTRACT

 

SIGNIFICANCE OF ANTIOXIDANTS IN MAINTAINING DAIRY AND BEEF ANIMALS’ HEALTH

Matrix Science Medica (MSM)
Author: Mughees Aizaz Alvi, Muhammad Saqib, Khurram Ashfaq, Imaad Rashid, Muhammad Haleem Tayyab, Muhammad Umar Ijaz

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

DOI: 10.26480/msm.02.2017.11.12

Oxidation and reduction reactions occurring inside the cell must be maintained in the state of equilibrium so that the integrity of cells can be maintained and production of the animals remains at optimum. If there is imbalance between redox reaction, health of the animals gets affected in terms of onset of various reproductive disorders and diseases like mastitis. A number of antioxidants are produced naturally inside the body but under stressful endogenous and exogenous environment, their production is hampered. Thus, supplementation of animals with antioxidants like vitamin C and Vitamin E in feed or parenteral administration is essential to keep the animal healthy to get maximum possible production.
Pages 11-12
Year 2017
Issue 2
Volume 1

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msm.02.2017.07.10

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DETECTION OF BIOFILM PRODUCTION BY STAPHYLOCOCCUS AUREUS AND IN-VITRO INHIBITION OF BIOFILM USING SERUM ANTIBODIES

Matrix Science Medica (MSM)
Author: Ali Raza, Abdul Ghaffar Qamar, Asad Manzoor, Misbah Ijaz, Khizar Hayat, Tayyab Rehmanand, Muhammad Shakeel ,Ghulam. Muhammad

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

DOI: 10.26480/msm.02.2017.07.10

The biofilm producing ability of Staphylococcus aureus has been implicated for development of different diseases in animals and humans. The presence of biofilms makes the bacterial population resistant to a wide range of antibiotics. Biofilms are also antigenic structures of the bacterial population. Therefore, the present study was planned to evaluate the biofilm-producing ability of S. aureus and in-vitro inhibition of biofilm production using serum samples from rabbits immunized with biofilm-producing S. aureus bacterin-toxoid. A total of 64 S. aureus isolates were harvested from lactating cows and buffaloes suffering from clinical and sub-clinical mastitis. The biofilm-producing ability of S. aureus isolates was determined by tube method and micro-plate assays. The rabbits were vaccinated using strong biofilm producing S. aureus bacterin-toxoid. The ability of serum antibodies to inhibit in-vitro biofilm production was assessed by performing a biofilm inhibition assay. The results showed that 71.87% and 56.25% of the isolates were positive for biofilm production in tube method and micro-plate assays, respectively. T he serum samples collected at days 30, 45 and 60 post-immunization completely inhibited the biofilm production by S. aureus. Our results suggested that both micro-plate assay and tube method can be used for determination of biofilm production, however micro-plate assay is quantitative, more accurate and reliable. The study also concluded that the antibodies produced against biofilm producing S. aureusbacterin-toxoid seems helpful to avert the attachment of bacteria, which may further implicate the better control of chronic infections.
Pages 7-10
Year 2017
Issue 2
Volume 1

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msm.02.2017.01.06

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MOLECULAR CHARACTERIZATION OF INFECTIOUS BURSAL DISEASE VIRUS FROM COMMERCIAL POULTRY IN PAKISTAN

Matrix Science Medica (MSM)

Author: Rai Shafqat Ali Khan, Mudasser Habib, Muhammad Salah Ud Din Shah, Waqas Ali, Zaheer Hussain, Zahid Ali Tahir

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

DOI: 10.26480/msm.02.2017.01.06

Infectious bursal disease (IBD) is an immunosuppressive disease of young, growing chickens which results in impaired growth or mortality of rearing flocks. In the current era there is a re-emergence of very virulent Infectious Bursal Disease Viruses (vvIBDV) and classical variant (cv) IBDV strains which increased the financial losses of poultry industry worldwide. Recent studies were conducted to characterize the existing vvIBDVs prevailing in Pakistan. The suspected samples were collected from the field outbreaks during the period from 2014–2017. IBDV was detected by RT-PCR. The sequences of VP2 gene (hyper variable region) were determined and available details were aligned with sequences submitted inGenBank. Phylogenetic analysis reveals that both vvIBDV and classical variant strains were circulating in different regions of Pakistan. In Indo-Pak isolates, the presence of virulent markers, amino acids (A222, I242, Q253, I256 and S299) and “Serine rich- heptapeptide” indicated the presence of very virulent viruses. The presence of T284A isan indicator of vvIBDVs in local poultry farms. More than 99% similarity of Pakistani isolates with Indian sequences reflects the trans-boundary spread of IBD. In recent studies amino acid, Glutamine (Q) is present at position 221 (as reported in previous studies) rather than Histidine (H) in Pakistani sequences. It is investigated that Glutamic acid (E) is located at position 300 in minor hydrophilic region III of VP2 protein in all reported Pakistani isolates. It is the unique feature of indigenous strains. This study will be useful in understanding the origin and pathotypes of IBDV circulating in Pakistan.
Pages 1-6
Year 2017
Issue 2
Volume 1

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msm.01.2017.30.33

ABSTRACT

 

Aging Mechanisms: Linking oxidative stress, obesity and inflammation

Matrix Science Medica (MSM)
Author: Ghazanfar Abbas, Amber Salman, Sajjad Ur Rahman, M. Khalil Ateeq, M. Usman, Sanaullah Sajid, Zaytoon Zaheer, Tayyaba Younas

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

DOI: 10.26480/msm.01.2017.30.33

Aging cannot be defeated in anyway in the world even having new and advanced technology. But molecular mechanism is a successful method to control aging. Many complex and multifunctional factors are the main cause of aging.
It is evident that the studies regarding cellular, genetic, and pathological and biochemical changes are exploring more and more pathways linking various diverse mechanism explaining aging. Implications of basic mechanisms of aging for improving both longevity and quality of life in human needs a clear understanding and takes a long time. However, reactive oxygen species (ROS) indicate a growing body even in the presence of fundamental mechanisms. According to oxidative stress theory, advanced and permanent addition of oxidative damage on critical aspects of aging process instigated by ROS influences. Telomeres theory is another, new aging theory that holds many promising possibilities for the field of anti-aging medicine. The theory was originated from the surge of technological breakthroughs in genetics and genetic engineering. Telomeres have also been found related to obesity. Obesity also leads to accelerated cellular processes. A “causative agent in aging” is considered inflammation that underlies a mechanism showing that for survival acute inflammatory response is necessary but long term exposure to different antigens than predicted by evolution cause low-grade inflammatory status which intern contributes to age-associated illness and death. The condition known as “inflammaging”.
Pages 30-33
Year 2017
Issue 1
Volume 1

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msm.01.2017.27.29

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A Reverse transcription-polymerase chain reaction (RT-PCR) based detection of foot and mouth disease in District Faisalabad, Pakistan during the Year 2016

Matrix Science Medica (MSM)
Author: Waqas Ali, Mudasser Habib, Sanaullah Sajid, Rai Shafqat Ali Khan, M. Usman Mazhar, Irfan Ullah Khan, Uneeb Saliha, Muhammad Farooq, M. Salah Ud Din Shah, Hafiz Muhammad Muzammil

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

DOI: 10.26480/msm.01.2017.27.29

Foot and mouth disease is an economically devastating disease of livestock that mainly effect cloven-hoofed animals i.e. sheep, goat, cattle, pig, buffalo, deer etc. The aim of this study was to determine the serotypes circulating in the region during 2016. Sampling was done from different outbreaks initially on the basis of clinical signs and later reverse transcriptase-polymerase chain reaction (RT-PCR) was employed for the confirmation of FMDV genome. Out of total 72 samples, 65 were found positive which were then serotyped into type O (n=30), Asia1 (n=19) and A (n=5). Some samples (n=5) were found positive for more than one serotype that were subjected to reverse transcriptase loop-mediated isothermal amplification assay (RT-LAMP) for serotype determination.
Pages 27-29
Year 2017
Issue 1
Volume 1

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msm.01.2017.22.26

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A Review of antihyperlipidemic effect of synthetic phenolic compounds

Matrix Science Medica (MSM)
Author: Sadaf Nawaz, Munazza shareef, Hina shahid, Misbah Mushtaq, Maliha sarfraz

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

DOI: 10.26480/msm.01.2017.22.26

It is seen that most of the deaths are occurring due to diseases of cardiovascular system. There is a significant impact of lifestyle changes on the quality of health. Utilization of food highly rich with saturated fat and having low fiber content is one of the factors of disarray in energy balance. It is now evinced that hyperlipidemia is depicted as a major risk factor for the premature development of atherosclerosis and its cardiovascular complications. The prevalence of obesity has doubled in the past 25 years; today, two-thirds of adults are overweight in the United State [1].
Pages 22-26
Year 2017
Issue 1
Volume 1

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