Published and Hosted by Wolters Kluwer , Medknow since 2019.

Medicine is the science and practice of the diagnosis, treatment and prevention of disease. Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness. Contemporary medicine applies biomedical science, biomedical research, genetics, and medical technology to diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, external splints and traction, medical devices, biologics, and ionizing radiation, amongst others. Matrix Science Medica (MSM) is an international medical journal open to physicians and scientists from the field of biomedicine and related research. We welcome all contributions that enhance or illuminate medical sciences. Matrix Science Medica (MSM) is a multidisciplinary medical journal published by the Zibeline International Publishing. The journal is peer-reviewed and published biannual in both paper and electronic form. The language of MSM is English.
Executive Editor in Chief

PROF. DR. A.A. ALTINTAS
Essen University Hospital
Germany
Editor in Chief

DR. YUSMAZURA ZAKARIA (PHD)
School of Health Sciences Health Campus
Universiti Sains Malaysia, Kota Bharu, Kelantan

PROF. DR. AHMAD ROHI GHAZALI
Biomedical Science Programme
School of Diagnostic & Applied Health Sciences
Faculty of Health Sciences
The National University of Malaysia
50300 Kuala Lumpur,Malaysia
Managing Editor

DR MUDASSIR HABIB
Principal Scientist Nuclear Institute
for Agriculture and Biology (NIAB)
Faisalabad, Pakistan

DR SYLVIA DAIM
Faculty of Medicine and Health Sciences
University Malaysia Sabah
Kota Kinabalu Sabah, Malaysia

DR CAROLINE SUNGGIP
Faculty of Medicine and Health Sciences
University Malaysia Sabah
Kota Kinabalu Sabah, Malaysia

DR ALI RAZA
Dept. of Clinical Medicine and Surgery
Faculty of Veterinary Science
The University of Agriculture
Faisalabad, Pakistan
Associate Editor

DR SULTAN ALI
Institute of Microbiology
Agriculture University Faisalabad
Pakistan

DR ASAD MANZOOR
Department of Clinical Medicine and Surgery
Faculty of Veterinary Science
University of Agriculture
Faisalabad, Pakistan

DR MISBAH IJAZ
Department of Clinical Medicine & Surgery
Faculty of Veterinary Science
University of Agriculture
Faisalabad, Pakistan

DR HASMAH ABDULLAH
School of Health Sciences
Health Campus
Universiti Sains Malaysia
Kota Bharu, Kelantan

DR NIK FAKHURUDDIN NIK HASSAN
School of Health Sciences
Health Campus
Universiti Sains Malaysia
Kota Bharu, Kelantan
Editorial Board Members

PROFESSOR. DR. URBAN JOHN ARNOLD D’ SOUZA
Faculty of Medicine and Health Sciences
University Malaysia Sabah
Kota Kinabalu Sabah, Malaysia

PROFESSOR DR. WAN HIMRATUL AZNITA BINTI WAN HARUN
Department of Oral & Craniofacial Sciences
Faculty of Dentistry, University Malaya
Kuala Lumpur, Malaysia

DR. BALAMURUGAN TANGIISURAN
School of Pharmaceutical Sciences,
Universiti Sains Malaysia.
Pulau Pinang, Malaysia

DR. SALIZAWATI MUHAMAD SALHIMI
School of Pharmaceutical Sciences
Universiti Sains Malaysia
Pulau Pinang, Malaysia

ASSOC. PROFESSOR. DR. DJULI ACUN DARMAWAN
Faculty of Medicine and Health Sciences
University Malaysia Sabah
Kota Kinabalu Sabah, Malaysia
DR. ZHANG YAXING
Department of Physiology
Zhongshan School of Medicine
Sun Yat-sen University
Guangzhou, People’s Republic of China

PROFESSOR. DR. SUBHA A/P BHASSU 
Sciences Faculty of Science
University of Malaya Kuala Lumpur, Malaysia

DR. WAN SYAIDATUL AQMA WAN MOHD NOOR
School of Biosciences and Biotechnology
Faculty of Science and Technology
Universiti Kebangsaan Malaysia
Bangi, Selangor, Malaysia

DR. BONG CHUI WEI
Institute of Biological Sciences Faculty of Science
University of Malaya Kuala Lumpur, Malaysia

DR. MOHAMMAD MUSTAFIZUR RAHMAN 
Kulliyah of Science International Islamic
University Malaysia,Jalan Sultan Ahmad Shah,
Kuantan, Pahang.

DR. JAMILAH SYAFAWATI BT YAACOB
Institute of Biological Sciences Faculty of
Science University of Malaya Kuala Lumpur, Malaysia

DR. TANG SWEE SEONG
Institute of Biological Sciences Faculty of
Science University of Malaya Kuala Lumpur, Malaysia

DR. SORAYYA BIBI MALEK BINTI MALEK ABD RASHID
Institute of Biological Sciences Faculty of Science
University of Malaya Kuala Lumpur, Malaysia

DR. KHANOM BINTI SIMARANI
Institute of Biological Sciences Faculty of
Science University of Malaya Kuala Lumpur, Malaysia

DR. TANMAY TIWARI
Associate Professor
Department of Anaesthesia,
King George’s Medical University Lucknow, India

PROF.DR.AISYAH ELLIYANTI MD
Faculty of Medicine Universitas Andalas
Padang, Indonesia

ASSOC. PROFESSOR. DR. MUNA BT SABRI
Faculty of Medicine and Health Sciences
University Malaysia Sarawak
Kota Samarahan Sarawak, Malaysia

JOSEPH ALMAZAN
Associate Professor
Nazarbayev University
PROFESSOR. DR. GHULAM MUHMMAD
Ex-Chairman Department of Clinical Medicine
and Surgery University of Agriculture Faisalabad
Pakistan

DR ASHLEY EDWARD ROY SOOSAY
Associate Professor
Paraclinical Sciences
Faculty of Medicine & Health Sciences
Universiti Malaysia Sarawak (UNIMAS)
94300 Kota Samarahan
Sarawak, Malaysia. 

PROF. DR. ADI PRAYITNO
Department of Dental and Oral Disease, Faculty of Medicine, University of Sebelas Maret, Surakarta, Indonesia

PROF. MOHAMMED AHAMED AHAMED ABUELNOR
Department of Human Anatomy- Faculty of Medicine & Health Sciences Gadarif University- Gadarif- Sudan.

DR. ADIL KHALIL HUSSIEN KHALIL
Department of Basic medical science, College of Medicine, Dar Al Uloom University, Riyadh, Kingdom of Saudi Arabia

Professor Dr Sandhya Babel
Distinguished Professor in Science and Technology, Thammasat University
School of Biochemical Engineering and Technology
Sirindhorn International Institute of Technology
Thammasat University
THAILAND

Dr. Jasmine E. Khairat
Institute of Biological Sciences
Faculty of Science
Universiti Malaya
50603 Kuala Lumpur, Malaysia

Professor Dr Zoumpourlis Vassilis
Research Director Head of the Biomedical Applications Unit, Institute of Chemical Biology, NHRF 48 Vassileos Constantinou Ave., Athens Greec

Professor Dr. Adel K. El-Naggar 
Department of Pathology, Division of Pathology/Lab Medicine, The University of Texas, MD Anderson Cancer Center, Houston, TX, USA

Assoc. Prof. Dr. Jamal Houssaini
Ph.D. (UM) Senior Fellow
Cardiovascular Advancement and Research Excellence Institute (CARE Institute). HiCoE Universiti Teknologi MARA
Associate Professor, Department of Medical Microbiology and Parasitology, Faculty of Medicine, Sungai Buloh Campus
Universiti Teknologi MARA (UiTM)

Dr Jo Ann Andoy Galvan
Senior Lecturer
School of Medicine
Faculty of Health & Medical Sciences Taylor’s University, Malaysia

ASSOCIATE PROF DR NORHAYATI RAMLI
Head Department of Bioprocess Technology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia

Dr. Nurul Nadia Abdul Razak
Office of The Executive Director,
Centre for Foundation Studies in Science Office
University of Malaya, 50603 Kuala Lumpur, Malaysia

Dr. Nur Hidayah Jamar
Department of Biological Sciences & Biotechnology
Faculty of Science & Technology
Universiti Kebangsaan Malaysia

PROF. AHMED OSUMANU HARUNA
Faculty of Agriculture
UNISSA, Brunei

Dr Muhammad Fattah bin Fazel
 Molecular Neuropharmacology
KPJ HEALTHCARE UNIVERSITY
Kajang, Selangor, Malaysia

Assoc Prof Dr Mohammad Mustafizur Rahman
Department of Marine Science, Kulliyyah of Science, International Islamic University Malaysia.
IIUM Kuantan Campus

Prof. Dr Tatyana Vlaykova
Medical Faculty, Trakia University,
Dept. Chemistry and Biochemistry
11 Armeiska Str., Stara Zagora, 6000
Bulgaria

Dr. Lee Wenn Chyau
Department of Parasitology,
Faculty of Medicine, Universiti Malaya
50603, Kuala Lumpur, Malaysia

REESHMAN SHAFA
Rotaract Club of Horizon Campus
Faculty of Science
Horizon Campus, Kurunegala, North Western Province, Sri Lanka

DR. THILOMI SAMARAKOON
Department of Zoology and Environmental Management
Faculty of Science
University of Kelaniya

MEDHISHA PASAN GUNAWARDENA
Senior Lecturer
Faculty of Science, Horizon Campus, Malabe
Kandy District, Central Province, Sri Lanka

PROFESSOR DR. SYED ALI RAZA NAQVI
IRSIP (Bart & the London School of Medicine & Dentistry, UK)
HEC Approved PhD Research Supervisor
Department of chemistry, GC University Faisalabad
Pakistan

ASSOCIATE PROFESSOR DR ROSAZLIN ABDULLAH
Institute of Biological Sciences
Faculty of Science
Universiti Malaya

DR. SHAHABUDDIN AHMMAD
Department of Mechanical Engineering
Faculty of Engineering
Universiti Malaya

YBHG. PROFESOR DR. YAP CHEE KONG
Faculty Of Science
Universiti Putra Malaysia

ASSO. PROF. DR. RABIHA BT HJ. SULAIMAN
Deputy Dean (Postgraduate, Research & Innovation)
Department of Food Technology
Faculty of Food Science and Technology
Universiti Putra Malaysia (UPM)




